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doi: 10.1016/j.immuni.2019.01.004 55 LalleGTwardowskiJGrinberg-BleyerY

En la piel, se une a los receptores de fibroblastos y activa los genes responsables del colgeno I, el colgeno III y la elastina, al mismo tiempo que calma la sealizacin inflamatoria que acelera el envejecimiento

doi: 10.1038/ncomms15069 147 TangWSaretSTianRWangHClaudioEMurphyPMet al

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[3] This balanced remodeling is attractive for a cosmetic goal in principle, but it is worth stressing that consistent with and attractive in principle are statements about plausibility, not about a demonstrated outcome in aging human skin by any given route